On May 13th and 21st, our research group hosted the grand thesis defense
sessions for the 2025 graduating class. After rigorous academic
presentations and defenses, Ph.D. candidate Chen Huaqing and master's
candidates Zhong Maiyi, Xiao Yang, and Deng Yuhan all successfully
passed their thesis defenses! With this, they have splendidly completed
their academic journey at Tsinghua University and are about to embark on
new chapters in their lives!
论文题目:《基于新型声敏剂的三阴性乳腺癌声动力免疫疗法》
创新点:本课题通过药物筛选出高效的新型声敏剂Flavesine G,声动力免疫疗法能有效的治疗三阴性乳腺癌。
论文题目:《基于核酸标签的多抗原筛选特异性TCR的方法及应用》
创新点:本课题研究提出高通量筛选抗原特异性TCR 的新方法“Tag-TCR”,结合寡核苷酸编码抗原技术与单细胞测序平台,弥补了现有研究在多抗原特异性TCR 并行筛选与精确配对能力方面的不足。
论文题目:《基于预训练多模态算法的TCR与BCR的综合分析与设计》
创新点:论文构建了一种利用多模态信息预测TCR和BCR结合抗原特异性的模型,在多个数据集和表位上的预测表现优于现有的方法。
论文题目:《PD 患者外周血α-syn特异性T细胞组学研究》
创新点:本论文通过研究帕金森病人外周血α-突触核蛋白特异的T细胞的特征和状态,探索帕金森病人的细胞免疫调节机制,通过体外激活筛选和单细胞测序等实验手段,系统解析了病人外周血的T细胞特征。发现了帕金森病外周T细胞免疫的异常,为探索其神经免疫调控机制打下良好基础。
The students sincerely thanked their advisor, Associate Professor Liu Xiao, for her guidance, appreciated the support of their labmates, and honored their own unwavering determination in research.
Congratulations on your graduation! May your future be radiant!