Culture dependent and independent approaches reveal the role of specific bacteria in human skin aging

2024-09-14

    Recently, Associate Professor Liu Xiao from the Institute of Biomedical and Health Engineering at Tsinghua Shenzhen International Graduate School and his collaborators used a multiple linear regression model, and predicted premature/delayed aging‐related microbial species, mainly Moraxella osloensis and Cutibacterium acnes. We also validated the biological functions of the host‐microbe interactions in vitro. Moraxella osloensis isolated from healthy skin regulates collagen metabolism and extracellular matrix assembly, and promotes cell senescence in human keratinocytes and fibroblasts, making it potentially applicable in the development of antiaging interventions.


Original link:https://onlinelibrary.wiley.com/doi/10.1002/imo2.26


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